Indian University Technology Database

Life Sciences

New Method of Diagnosis of Anaemia and Lead Toxicity
Ref No:KARB01/018
Sub Class: Biology & Biotechnology
Technology Outcome: Product
Development Status: Advanced Research
IPR Status: Not Patented
Technology Description: An enzyme known as Heme-Regulated Inhibitor (HRI) plays a pivotal role in the synthesis of haemoglobin. When the iron level in the body goes down, HRI inhibits the synthesis of haemoglobin. From the experiments it has been determined that the level of HRI can be very sensitive indicator to monitor the degree of anaemia as well as lead toxicity in comparison to other existing methods. This development, for the first time indicated the possibility of developing a HRI based probe for the detection & diagnosis of anaemia by Western Blot & RT- PCR. The application area is diagnosis of clinical, hematological disorders of various kinds namely iron deficiency, anaemia, drug toxicity, lead poisoning and blood cancer. The competitive advantages are: (i) This method is more sensitive as compared to existing methods (ii) It may have a prognostic value.
Technology owner:
Suggested transfer means:
Type of technology partner sought: Medical institutes or hospitals or pharmaceuticals companies
Geographical areas where partners are sought:
Source: University of Pune